The response from some: It better be.
At a closed-door Democratic caucus meeting the frustration was palpable, according to people who were in the room, despite Pelosi's efforts to frame the results as evidence of incremental Democratic progress in deep red districts.
Although the race was widely viewed as a referendum on President Donald Trump, he was rarely discussed by either candidate, and House Democrats were rattled that the attack ads casting the 77-year-old Pelosi as a San Francisco liberal proved so potent.
Prior to Georgia and South Carolina, Democrats fell in special races in Kansas in April and Montana in May.
We would dispute the first half of that - joining the GOP in passing a profoundly unpopular health care bill, voting for massive giveaways to the rich and banning Muslims from entering the country are no ticket to taking over Congress in next year's midterm elections.
"We'd better take a good, long, strong look in the mirror and realise that the problem is us; it's the party", OH representative Tim Ryan said Wednesday morning as he left a closed-door meeting of the Democratic Caucus in the Capitol.
The moderate New York Democrat said she had talked to a number of House Democrats since last night's defeat and some expressed concerns about keeping the same leadership team.
House Minority Leader Nancy Pelosi of Calif. speaks to reporters during a news conference on Capitol Hill in Washington, Thursday, June 22, 2017. "That would be very bad for the Republican Party - and please let Cryin' Chuck stay!" he tweeted.
It was a bitter loss for the Democrats, some of whom are openly speculating about whether House Minority Leader Nancy Pelosi has become a liability.More news: Nevada's Heller becomes 5th GOP senator opposed to health bill
Some Democrats have blamed Pelosi for the party's loss in the Georgia special election on Tuesday. "We're a family. We're going to have those discussions". What if they dislike Democrats more than they do the president? So it's time for change. I think it's time for a new generation of leadership. But to win in 2018, Democrats will have to flip GOP-held House districts to their side. "At least another decade", Gingrich said.
Progressives certainly aren't cozy with Pelosi, and have called for her to no longer serve as a Democratic party figurehead. "I thrive on competition, and I welcome the discussion", she said.
Neera Tanden, the head of the progressive think tank Center for American Progress, tweeted that Democrats needed to hit back much harder.
Progressives made this about Trump, even if Ossoff didn't, and they lost. "We've seen her run circles around (former House Speaker) John Boehner and get things done that nobody thought Democrats could do in the minority". Most notably, Karen Handel won a Georgia Congressional seat against "dream" Democrat candidate Jon Ossoff.
Any House race that generates $50 million in spending - it was the costliest in history - is hardly a generic laboratory and therefore the results are subject to over-interpretation.
"She's easy to demonize".
Democrats don't lack a message.
The Handel victory will give the Republicans and the White House a psychological boost and likely keep them together in the coming months as they try to pass major pieces of their and Trump's agenda.