The Merseyside club will know they need to be at their best to keep out a unsafe Man City strike-force of Gabriel Jesus and Sergio Aguero, with the latter scoring in his last five consecutive league games against Liverpool.
Alvaro Jimenez scored the victor with a long-range shot in the 83rd minute, not long after Guerrero had missed a penalty-kick that could have given the hosts the lead.
It took two goals in the final 20 minutes to overcome newly-promoted Brighton & Hove Albion on the opening day of the season, and another late goal was required to rescue a point against Everton in their first home game of the campaign. I saw the goalie already and obviously it's not that bad.
Jurgen Klopp has disputed Sadio Mane's sending-off in Liverpool's defeat to Manchester City. We couldn't keep him - he was shocked about the situation.
Manchester City are continuing to dominate without taking their chances
The Reds started the game well but their poor defense helped City take the lead.
"It is unlucky, an accident". Fair play to them, we looked like Arsenal when they turned up at Anfield a couple weeks ago.
"The keeper comes out".
"He is a very good football player", Klopp said.
"That means you want to have him on the pitch as often as possible. What would have happened if we had played 11 against 11?"
Now Champions League is coming for both teams next week as Liverpool will host a talented Spanish side of Sevilla while Man City will travel to Holland to face Feyernoord.
Manchester City goalkeeper Ederson has allayed concerns over his condition after being carried off during Saturday's match against Liverpool but he could still miss his team's Champions League opener.More news: Kim Jong-un celebrates North Korea's nuclear scientists