After the sending off, De Bruyne set up Jesus for an easy header, and Liverpool seemed to be happy about going down to the half time break with only two goals to try and fight back from.
Should Sadio Mane have seen a red? Referee Moss is quick to show a red card. "His eyes are on the ball". Last season he shot 15 or 16 times against the post.
As Thierry Henry pointed after the match, the condition Ederson was in, had an influence on referee's Jon Moss decision. He didn't need to give a red card.
Controversial, but worthy of a send off.
It was punishment enough that Liverpool lost a key player in the 37th minute and went on to be humiliated 5-0. Mane's sympathisers will argue that he was entitled to go for the ball and that, as Guardiola conceded, it was an accidental collision.
It was Liverpool's turn to fret next when Ragnar Klavan was caught in possession deep in his own half by Jesus, who forced a corner from which John Stones drew a reflex stop from Mignolet.
Mignolet believes Liverpool can bounce back from City defeat
The Argentine also made a small piece of history by scoring his 124th in the Premier League, making him the top-scoring non-European player in the top flight's 25-year history.
Questions must be asked about City's rout but in particular a first goal where Liverpool's centre-backs were not even in the same postal district.
City then shifted to a 4-3-3 in the victory over Bournemouth, with a central triumvirate of Kevin De Bruyne, David Silva and Fernandinho - a pair of No.10s and a box-to-box midfielder.
City had another effort ruled out when Aguero put the ball in the net early in the second half. The Argentina forward rounded Mignolet and tucked home his sixth goal in as many league home appearances against Liverpool.
If the South American flavour continues to bloom this way, there's no reason why the two don't deserve to play together. Both teams did not defend really well.
Not entirely, though. There is a way of playing with 10 men and this was absolutely not it.
Jesus then had a header from a curling De Bruyne cross from the left ruled out for offside, before having an assist moments later.More news: Drone video shows destruction in one Florida city directly in Irma's path