However, the German said the playmaker would not feature in he lunch-time kick-off at the Etihad.
Klopp says that he is set for Champions League duty this week. "I think we are going to swap", he added.
"Yes, he went to the national team and trained normally, but now we have to prepare for a normal season so we have seven games [before the next global break] and we saw training this morning and thought "OK, maybe we should use him immediately" because he was really good, but that doesn't make sense".
"I wouldn't have wanted to play for a reason like this, an injury to a team-mate, but you always have to be prepared". "It was a good conversation".
Raheem Sterling will be unable to play against his former side against being sent off about Bournemouth.
He trained with the rest of the squad on Thursday.
Shortly after the final whistle blew, Manchester City teammate Benjamin Mendy uploaded a picture of Ederson looking worse for wear after Mane's dangerously high challenge. "He is good in small spaces, really good in big spaces, a good dribbler, a good passer - there's a lot of things I really like". He had a little problem in his calf.More news: UK govt warns of Brexit chaos if lawmakers don't back bill
"Do I think that somebody could have [a complaint]?"
There is no appetite at Anfield to contest the Senegal international's sending-off in a game they went on to lose 5-0.
"We have to take the first 20 minutes and how we played before the global break and take it into the next game", said Mignolet. Now, unfortunately, we've lost him, but we will try and get him fit as soon as possible.
N'Golo Kante was a key member of Leicester's title-winning team two years ago and the Chelsea midfielder returned to haunt his old club with a 50th minute long-range strike.
Eliaquim Mangala could return to first-team action if Guardiola decides to revert to playing three at the back, but given his manager's comments about needing to work on the Frenchman's "weakness in the build-up", that seems unlikely. Grumbling about the finishing of youthful attackers and questionable man-management of one of the most lethal strikers in the game are uncomfortably prevalent themes a year into his tenure at City. "Zero chance", Guardiola said.
"He knows that he's a Liverpool player, so he said nothing".