He was quick to explain why he did. Since then, Cowboys owner Jerry Jones said he would punish players for disrespecting the flag, and Miami Dolphins owner Stephen Ross said he wants the players to stand.
But the former governor of IN and his wife, wearing a Manning No 18 jersey, left Lucas Oil Stadium after the national anthem, following instructions from President Donald Trump after a number of San Francisco 49ers players took a knee during the anthem.
Pence then flew from Indianapolis to Los Angeles on Sunday, which took about four hours and 45 minutes, costing about $142,500.
These developments came the same day that Colin Kaepernick was quoted as saying he would stand during the national anthem if signed by an NFL team this season. He tweeted the same photo from his account when he was the governor of IN on November 23, 2014.
A member of the vice president's staff told the reporters that "there may be an early departure from the game".
Football players have been taking a knee in silent protest since past year, demonstrating against police brutality and racial injustice.
MSU redshirt Freshman Noah Davis said, "I like what Dallas did last weekend when they kneeled right before the anthem was played".
It's a return to the theme of Trump's weekend tweet that "only one thing will work" in dealing with North Korea.
In response, some players called it a "PR stunt." the NFL Players' Association, which represents all NFL players, released a statement soon after Pence's protest.
Trump writes that National League Football players should "Stand for Anthem or sit for game!"
The NFL Players Association issued a statement on Sunday reiterating its support of players' rights to express their views.