Read on for a full preview of the clash, along with team news, scheduling details and viewing information.
Unsurprisingly Barcelona looked to dominate the early possession and control the tempo of the game, but it was the home side who started the brighter.
When asked if he had agreed it with Messi this week, he replied: "These are internal decisions of the coach".
The Telegraph reported in the summer the club were eager to pen Hazard down to a new contract at Chelsea.
Unless CSKA Moscow put seven past Manchester United in the final round of Champions League group games, Jose Mourinho's men are through to the knockout stages despite their 1-0 defeat at Basel.
Messi's hesitancy to commit his future to Barcelona after 16 years with the club has left fans increasingly nervous, especially after the departure of Brazilian star Neymar to Paris Saint-Germain in the close season. Starting on the bench, Juventus looked like they would be able to turn to Mandzukic in the second half to help push for a much-needed late goal. Paulo Dybala meanwhile, the man widely acknowledged as the Argentine's footballing heir, almost opened the scoring after a darting run of his own. Hazard's burgeoning partnership with the Spaniard has been a huge positive for Chelsea this season but he had fun without him here too. These sides have met ten times and there is little to separate them as Barcelona have four wins to Juve's three with the remaining three ending in stalemates.
Dybala reflected on his late chance and said on the club's website: "We had our chances tonight and it's a pity that shot in injury time didn't go in". Barca picked up a 3-0 win over Leganes in their most recent La Liga fixture, while Juve are coming off a shocking 3-2 defeat against Sampdoria over the weekend.
Do you think Juventus can hand Barca their first loss of the 2017/18 UCL campaign?
Paulinho's other notable contribution was to be booked for diving in the penalty area while Luis Suarez was largely anonymous. When you play games like this, everyone needs to defend.
The 30-year old has been in a great form this season. Created some inspiration and nearly scored the winner in stoppage time but was denied by Marc-Andre ter Stegen. And because they weren't capable of beating Sporting in Lisbon, they have not yet qualified for last-16 of Champions League.
But even with their bright start to the second half, it wasn't until Messi stepped onto the pitch that Barcelona looked truly dangerous.