As mentioned above, if Liverpool can sew up the holes they have in defense, the Reds could make a real go of it. The principle question at the moment is who will be wearing the #1 jersey at Anfield?
City have the best squad in England, and Guardiola's side should be able to win against Rafael Benitez's side with ease.
It was a similar message from Antonio Conte following Chelsea's FA Cup third round replay win over Norwich on Wednesday with the Blues boss bemoaning the fact that his side have to travel to Brighton tomorrow lunchtime. The Magpies look out of sorts and the team is not bonding together. There have been somewhat inconsistent performances from these midfield stars for Arsenal this season, and apart from Ramsey, nobody has been convincing enough to warrant a place in the long-term future. The Cityzens, despite losing their unbeaten streak, remain the best team in the league, and will want to bounce back quickly from their defeat to Liverpool.
In the past it has often fallen to Sergio Aguero to score the goals that have brought City their success, but in this campaign he has actually been outscored by Raheem Sterling.
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Arguably there is no bigger contributor to that offense this season than Egyptian export Mohamed Salah.
Fernandinho has enjoyed a new lease of life under Pep Guardiola and has excelled at the base of City's midfield this season and even netted twice.
Saturday evening offers the runaway leaders the chance to put that loss behind them when Newcastle visit the Etihad Stadium.
The influential David Silva missed the reverse fixture due to the premature birth of his son. When the plan is working, you get results like a 4-3 victory over a previously undefeated Manchester City. Perhaps supporters will always be worried that their time in the sun is coming to an end, scared of the pride before a fall.
If City do fail from this position, at least they can say they had never counted their chickens too early or that they had seen the inevitable crash happening.
Fernandinho has won a Premier League title and two League Cups at City.