Indeed, they could well break the record for wins by a club in a single top-flight season, which is presently held by Tottenham Hotspur (31 in 1960-61). Two of the most potent attacks in Premier League history - Cristiano Ronaldo, Rooney and Tevez v Aguero, Silva and De Bruyne - lead to plenty of goals.
At last, Manchester City's players can enjoy a serene Premier League title triumph.
It is the team's first league title since 2014.
City players were left celebrating the victory across the continent as they had travelled overseas after defeating Spurs on Saturday. Real Madrid, years ago, lost five games in a row and didn't win the league.
Pep Guardiola's side are expected to lift the Premier League trophy and be given their winners medals in their final home game of the season against Huddersfield Town on May 6.
"Bogey, double-bogey, birdie", said Guardiola.
Given City's capitulation against United last week, Tottenham's goal changed the dynamic of the game and the hosts were camped in City's half for the opening 20 minutes after the resumption.
The dominant start was deservedly rewarded with a 22nd-minute lead and it was not out of the usual Manchester City playbook.
Pep Guardiola saluted his champions-elect for an "outstanding season" after they edged ever closer to the title.
Chelsea kept their faint hopes of Champions League football next season alive by closing to within 7 points of Spurs with a stunning 8-minute fightback to deepen Southampton's predicament in the bottom three. It is the most hard thing.
We think it's pretty nice but what who exactly will be wearing it next season? The amount of goals, chances and points, to do that in the Premier League, with the contenders we have, is because the players are so good.
"I had a feeling when I woke up this morning but it's a different experience when you're waiting for a team to lose".
"Mo knows what this means and the way we play suits him", added Klopp.
The home side are just three points above the relegation zone, after a run of three defeats in their last five outings in the top-flight.
"After that, in a competition like the Champions League, with decisions and good opponents happen in both games we can not complete closely against Liverpool but for the rest of the season, even the game against Wigan with 10 against 11 we were outstanding".
A tight game then, this, with Roy Keane, David Beckham and Ryan Giggs never fully going at a City team capable of punishing space in an instant.