Earlier, Labour's Emily Thornberry condemned a "horrific massacre".
Iran's foreign minister has lashed out at the Israeli regime for pursuing a repressive approach to peaceful protests by Palestinians demanding right to return to their motherland.
"It is in everyone's interests for peace and stability to prevail in Israel and the occupied Palestinian territories".
The opening of the U.S. embassy in Jerusalem on Monday also meant the symbolic recognition of Jerusalem as the Israeli capital‚ a move which has been condemned internationally as provocative and a threat to peace in the region.
Israel said it is defending its border and accuses Hamas of trying to carry out attacks under the cover of the protests.
Monday's protests were timed to mark the anniversary of Israel's creation in 1948 and the hundreds of thousands of Palestinians who subsequently fled their homes or were displaced in the war that followed.
A Palestinian woman walks through black smoke from burning tires during a protest on the Gaza Strip's border with Israel Monda.
His daughter, Ivanka, unveiled the seal of the embassy, and her husband, Jared Kushner, said in his address: "When President Trump makes a promise he keeps it".
The protests were directed at a crippling blockade imposed by Israel and Egypt after the Islamic militant group seized power in Gaza in 2007.
The new USA embassy was opened on the 70th anniversary of the state of Israel being established.
A spokesman for the Kremlin said: "From the very beginning, Moscow expressed concern actions by the United States could provoke tensions in the Middle East".
Asked if the White House feared the ongoing protests and killings undermined the plan, Shah said, "No, we don't".
The large number of wounded placed a new burden on Gaza's already struggling hospitals, where key medicines and surgical supplies were lacking even before the latest bloodshed, in part because of the border closures. Demonstrators gathered at several locations on the fenced enclave's border.
Netanyahu defended his military, saying: "Every country has an obligation to defend its borders".
"Now that the two-state solution is over, perhaps the region can start looking at alternative visions for a genuine peace that actually represents the rights and claims of all people living on this land", Nassar writes.
Why is the embassy so controversial?
Shapiro criticized the media's "attempt" to link the violence with the embassy's opening.
While Monday's protests in Gaza were organized to coincide with the embassy opening, the demonstrations are about far more than the change in status of the United States consulate building in Jerusalem.