Both players kept their places against Egypt and scored again, alongside an own goal.
Does Russia clinch a quarterfinal berth, or can Egypt get the upset?
Egypt counts right back Ahmed Fathi as a minor doubt with muscular tightness, while team manager Ihab Leheta is keen to present a united front.
Egypt looked a shadow of their disciplined self in a second half to forget.
39- Marwan Mohsen flicks a header towards goal! When Salah pulled free at the back post, Zhirkov made the clearance, scrambling the ball over his own bar.
19-Denis Cheryshev smashes a shot just over!
Egypt's travelling army of fans have not been hard to see or hear in St Petersburg over recent days, repeatedly bursting into their hero's Liverpool anthem with the gusto of long-time Kop season ticket holders.
It's all about Salah tonight!
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Egypt will most likely go with a 4-2-3-1 formation with Sam Morsy and Mohamed Elneny playing in central midfield.
Remarkably Cheryshev was not even expected to be a starter in the tournament, but has taken full advantage of Alan Dzagoev's unfortunate injury to cement his place in the side.
Check out the atmosphere at the Saint Petersburg stadium!
After a pedestrian first half in which each side managed only one shot on target, Russia's breakthrough came in farcical circumstances within two minutes of the restart.
Big news for Egypt!
The hype was as high as one would expect leading up to Salah's start on Tuesday, but what could have been a fairy-tale comeback became a story of underperformance. The Pharaoh's talisman is back!
Here's how to watch Russian Federation vs. Egypt online.
Whatever was to unfold at Krestovsky Stadium - ultimately nearly certainly a swift World Cup exit via a chastening 3-1defeat for his country - Salah would be in no position to influence the outcome.
The hosts face the north Africans in St Petersburg on Tuesday and defeat would nearly certainly condemn Egypt to an early exit. Playing in front of their home crowd, Russian Federation have looked imperious on the attack and assured in defence, and will be boosted by the home support to ensure they become the first team to qualify for the Round of 16 with a comfortable win. A positive result in this match is crucial for Egypt to keep its hopes of advancing to the 2018 World Cup knockout stage alive. - Russia's 5-0 win against Saudi Arabia was the second-biggest by a host nation in its opening match at a World Cup tournament, after Italy beating the US 7-1 in 1934. Substitute Denis Cheryshev grabbed a brace in the game including a stunning strike to give the hosts a vital three points. The superstar goal scorer didn't play in the first group stage game. Egypt lost their first match against Uruguay and they will now look to fix their campaign.